FeaturedLipidomic profiling reveals age-dependent changes in complex plasma membrane lipids that regulate neural stem cell aging
Zhao X, Yan X, Contrepois K, Vallania F, Ellenberge M, Kashiwagi CM, Gagnon SD, Siebrand CJ, Cabruja M, Traber GM, McKay A, Hornburg D, Khatri P, Snyder MP, Zare RN, Brunet A
bioRxiv · 2022
FeaturedCell-type-specific metabolic profiling achieved by combining Desorption Electrospray Ionization Mass Spectrometry Imaging and immunofluorescence staining
Yan X*, Zhao X* (equal contribution), Zhou Z, McKay A, Brunet A, Zare RN
Analytical Chemistry · 2020
FeaturedSLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice
Zhao X, Petrashen AP, Sanders JA, Peterson AL, Sedivy JM
Aging Cell · 2019
FeaturedReduced expression of MYC increases longevity and enhances healthspan
Hofmann JW*, Zhao X* (equal contribution), De Cecco M, Peterson AL, Pagliaroli L, Manivannan J, Hubbard GB, Ikeno Y, Zhang Y, Feng B, Li X, Serre T, Qi W, Van Remmen H, Miller RA, Bath KG, de Cabo R, Xu H, Neretti N, Sedivy JM
Cell · 2015
Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging
Leeman DS, Hebestreit K, Ruetz T, Webb AE, McKay A, Pollina EA, Dulken BW, Zhao X, Yeo RW, Ho TT, Mahmoudi S, Devarajan K, Passegué E, Rando TA, Frydman J, Brunet A
Science · 2018
Death by transposition – the enemy within?
Sedivy JM, Kreiling JA, Neretti N, De Cecco M, Criscione SW, Hofmann JW, Zhao X, Ito T, Peterson AL
Bioessays · 2013
Nuclear protein accumulation in cellular senescence and organismal aging revealed with a novel single-cell resolution fluorescence microscopy assay
De Cecco M, Jeyapalan J, Zhao X, Tamamori-Adachi M, Sedivy JM
Aging (Albany NY) · 2011
Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB-18, an endophyte of Artemisia annua
Gu W, Ge HM, Song YC, Ding H, Zhu HL, Zhao X, Tan RX
Journal of Natural Products · 2007